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Genomic encoding of transcriptional burst kinetics

Genomic encoding of transcriptional burst kinetics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A572650602

Genomic encoding of transcriptional burst kinetics

About this item

Full title

Genomic encoding of transcriptional burst kinetics

Publisher

Nature Publishing Group

Journal title

Nature, 2019, Vol.565 (7738), p.251

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

Mammalian gene expression is inherently stochastic.sup.1,2, and results in discrete bursts of RNA molecules that are synthesized from each allele.sup.3-7. Although transcription is known to be regulated by promoters and enhancers, it is unclear how cis-regulatory sequences encode transcriptional burst kinetics. Characterization of transcriptional b...

Alternative Titles

Full title

Genomic encoding of transcriptional burst kinetics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A572650602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A572650602

Other Identifiers

ISSN

0028-0836

DOI

10.1038/s41586-018-0836-1

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