The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
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Nature Publishing Group
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English
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Nature Publishing Group
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Inactivation of ARID1A and other components of the nuclear SWI/SNF protein complex occurs at very high frequencies in a variety of human malignancies, suggesting a widespread role for the SWI/SNF complex in tumour suppression.sup.1. However, the underlying mechanisms remain poorly understood. Here we show that ARID1A-containing SWI/SNF complex (ARI...
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The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
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TN_cdi_gale_infotracmisc_A573117625
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A573117625
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ISSN
0028-0836
DOI
10.1038/s41586-018-0658-1
