Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphoma...
Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome
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Nature Publishing Group
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English
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Nature Publishing Group
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Subcutaneous panniculitis-like T cell lymphoma (SPTCL), a non-Hodgkin lymphoma, can be associated with hemophagocytic lymphohistiocytosis (HLH), a life-threatening immune activation that adversely affects survival.sup.1,2. T cell immunoglobulin mucin 3 (TIM-3) is a modulator of immune responses expressed on subgroups of T and innate immune cells. W...
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Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome
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TN_cdi_gale_infotracmisc_A573206214
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A573206214
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ISSN
1061-4036
DOI
10.1038/s41588-018-0251-4