Cytokinesis defects and cancer
Cytokinesis defects and cancer
About this item
Full title
Cytokinesis defects and cancer
Author / Creator
Publisher
Nature Publishing Group
Journal title
Nature Reviews Cancer, 2019, Vol.19 (1), p.32
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Whole-genome and centrosome duplication as a consequence of cytokinesis failure can drive tumorigenesis in experimental model systems. However, whether cytokinesis failure is in fact an important cause of human cancers has remained unclear. In this Review, we summarize evidence that whole-genome-doubling events are frequently observed in human canc...
Alternative Titles
Full title
Cytokinesis defects and cancer
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A573358972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A573358972
Other Identifiers
ISSN
1474-175X
DOI
10.1038/s41568-018-0084-6
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