PSPC1 mediates TGF-[beta]1 autocrine signalling and Smad2/3 target switching to promote EMT, stemnes...
PSPC1 mediates TGF-[beta]1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
About this item
Full title
Author / Creator
Publisher
Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Activation of metastatic reprogramming is critical for tumour metastasis. However, more detailed knowledge of the underlying mechanism is needed to enable targeted intervention. Here, we show that paraspeckle component 1 (PSPC1), identified in an aberrant 13q12.11 locus, is upregulated and associated with poor survival in patients with cancer. PSPC...
Alternative Titles
Full title
PSPC1 mediates TGF-[beta]1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A580380426
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A580380426
Other Identifiers
ISSN
1465-7392
DOI
10.1038/s41556-018-0062-y
