Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of en...
Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of engineered Escherichia coli cell factory
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Publisher
BioMed Central Ltd
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Language
English
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BioMed Central Ltd
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Bear bile powder is a valuable medicinal material characterized by high content of tauroursodeoxycholic acid (TUDCA) at a certain ratio to taurochenodeoxycholic acid (TCDCA). We had created an engineered E. coli harboring two-step bidirectional oxidative and reductive enzyme-catalyzing pathway that could rapidly convert TCDCA to TUDCA at a specific...
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Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of engineered Escherichia coli cell factory
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TN_cdi_gale_infotracmisc_A581360936
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A581360936
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ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-019-1076-2
