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Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibi...

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A596603774

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition

About this item

Full title

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition

Publisher

BioMed Central Ltd

Journal title

Journal for ImmunoTherapy of Cancer, 2019, Vol.7 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Immune checkpoint inhibitors (ICIs) for solid tumors, including those targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), have shown impressive clinical efficacy, however, most patients do not achieve durable responses. One major therapeutic obstacle is the immunosuppressive tumor immune microenvironme...

Alternative Titles

Full title

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A596603774

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A596603774

Other Identifiers

ISSN

2051-1426

E-ISSN

2051-1426

DOI

10.1186/s40425-019-0698-6

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