Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibi...
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition
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Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Contents
Immune checkpoint inhibitors (ICIs) for solid tumors, including those targeting programmed cell death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), have shown impressive clinical efficacy, however, most patients do not achieve durable responses. One major therapeutic obstacle is the immunosuppressive tumor immune microenvironme...
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Full title
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition
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TN_cdi_gale_infotracmisc_A596603774
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A596603774
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1186/s40425-019-0698-6