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An intrinsic role of IL-33 in T.sub.reg cell-mediated tumor immunoevasion

An intrinsic role of IL-33 in T.sub.reg cell-mediated tumor immunoevasion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A609181655

An intrinsic role of IL-33 in T.sub.reg cell-mediated tumor immunoevasion

About this item

Full title

An intrinsic role of IL-33 in T.sub.reg cell-mediated tumor immunoevasion

Publisher

Nature Publishing Group

Journal title

Nature immunology, 2020-01, Vol.21 (1), p.75

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

Regulatory T (T.sub.reg) cells accumulate into tumors, hindering the success of cancer immunotherapy. Yet, therapeutic targeting of T.sub.reg cells shows limited efficacy or leads to autoimmunity. The molecular mechanisms that guide T.sub.reg cell stability in tumors remain elusive. In the present study, we identify a cell-intrinsic role of the ala...

Alternative Titles

Full title

An intrinsic role of IL-33 in T.sub.reg cell-mediated tumor immunoevasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A609181655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A609181655

Other Identifiers

ISSN

1529-2908

DOI

10.1038/s41590-019-0555-2

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