Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and de...
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning
About this item
Full title
Author / Creator
Eckenweber, Florian , Medina-Luque, Jose , Blume, Tanja , Sacher, Christian , Biechele, Gloria , Wind, Karin , Deussing, Maximilian , Briel, Nils , Lindner, Simon , Boening, Guido , von Ungern-Sternberg, Barbara , Unterrainer, Marcus , Albert, Nathalie L , Zwergal, Andreas , Levin, Johannes , Bartenstein, Peter , Cumming, Paul , Rominger, Axel , Höglinger, Günter U , Herms, Jochen and Brendel, Matthias
Publisher
BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
BioMed Central Ltd
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More information
Scope and Contents
Contents
P301S tau transgenic mice show age-dependent accumulation of neurofibrillary tangles in the brainstem, hippocampus, and neocortex, leading to neuronal loss and cognitive deterioration. However, there is hitherto only sparse documentation of the role of neuroinflammation in tau mouse models. Thus, we analyzed longitudinal microglial activation by sm...
Alternative Titles
Full title
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning
Authors, Artists and Contributors
Author / Creator
Medina-Luque, Jose
Blume, Tanja
Sacher, Christian
Biechele, Gloria
Wind, Karin
Deussing, Maximilian
Briel, Nils
Lindner, Simon
Boening, Guido
von Ungern-Sternberg, Barbara
Unterrainer, Marcus
Albert, Nathalie L
Zwergal, Andreas
Levin, Johannes
Bartenstein, Peter
Cumming, Paul
Rominger, Axel
Höglinger, Günter U
Herms, Jochen
Brendel, Matthias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A631893011
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A631893011
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-020-01883-5
