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Direct measurement of lipid membrane disruption connects kinetics and toxicity of A[beta]42 aggregat...

Direct measurement of lipid membrane disruption connects kinetics and toxicity of A[beta]42 aggregat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A637739050

Direct measurement of lipid membrane disruption connects kinetics and toxicity of A[beta]42 aggregation

About this item

Full title

Direct measurement of lipid membrane disruption connects kinetics and toxicity of A[beta]42 aggregation

Publisher

Nature Publishing Group

Journal title

Nature Structural and Molecular Biology, 2020, Vol.27 (10), p.886

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

The formation of amyloid deposits in human tissues is a defining feature of more than 50 medical disorders, including Alzheimer's disease. Strong genetic and histological evidence links these conditions to the process of protein aggregation, yet it has remained challenging to identify a definitive connection between aggregation and pathogenicity. U...

Alternative Titles

Full title

Direct measurement of lipid membrane disruption connects kinetics and toxicity of A[beta]42 aggregation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A637739050

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A637739050

Other Identifiers

ISSN

1545-9993

DOI

10.1038/s41594-020-0471-z

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