KRAS4A directly regulates hexokinase 1
KRAS4A directly regulates hexokinase 1
About this item
Full title
KRAS4A directly regulates hexokinase 1
Author / Creator
Publisher
Nature Publishing Group
Journal title
Nature, 2019, Vol.576 (7787), p.482
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
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More information
Scope and Contents
Contents
The most frequently mutated oncogene in cancer is KRAS, which uses alternative fourth exons to generate two gene products (KRAS4A and KRAS4B) that differ only in their C-terminal membrane-targeting region.sup.1. Because oncogenic mutations occur in exons 2 or 3, two constitutively active KRAS proteins--each capable of transforming cells--are encode...
Alternative Titles
Full title
KRAS4A directly regulates hexokinase 1
Authors, Artists and Contributors
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Record Identifier
TN_cdi_gale_infotracmisc_A649563630
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A649563630
Other Identifiers
ISSN
0028-0836
DOI
10.1038/s41586-019-1832-9
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