Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H.sub.2O.su...
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H.sub.2O.sub.2.sup.- production
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Nature Publishing Group
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English
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Nature Publishing Group
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Although the pathological contributions of reactive astrocytes have been implicated in Alzheimer's disease (AD), their in vivo functions remain elusive due to the lack of appropriate experimental models and precise molecular mechanisms. Here, we show the importance of astrocytic reactivity on the pathogenesis of AD using GiD, a newly developed anim...
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Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H.sub.2O.sub.2.sup.- production
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TN_cdi_gale_infotracmisc_A650878575
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A650878575
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ISSN
1097-6256
DOI
10.1038/s41593-020-00735-y
