Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
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Author / Creator
Publisher
Nature Publishing Group
Journal title
Language
English
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Publisher
Nature Publishing Group
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Scope and Contents
Contents
Intestinal organoids derived from single cells undergo complex crypt-villus patterning and morphogenesis. However, the nature and coordination of the underlying forces remains poorly characterized. Here, using light-sheet microscopy and large-scale imaging quantification, we demonstrate that crypt formation coincides with a stark reduction in lumen...
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Full title
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation
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Record Identifier
TN_cdi_gale_infotracmisc_A668389715
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A668389715
Other Identifiers
ISSN
1465-7392
DOI
10.1038/s41556-021-00700-2
