HIF1[alpha] is dispensable for oocyte development and female fertility in mice
HIF1[alpha] is dispensable for oocyte development and female fertility in mice
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Author / Creator
Chen, Yujia , Du, Siyu , Huang, Zhenyue , Han, Longsen and Wang, Qiang
Publisher
PeerJ. Ltd
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Language
English
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PeerJ. Ltd
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Background It has been thought that oocyte may develop in a low oxygen environment, as changes in follicle structure and formation of a fluid-filled antrum. The survival of hypoxic tissues is controlled by hypoxia-inducible factors (HIFs) that are activated in a low oxygen state. HIF1[alpha] is expressed in mature mouse oocytes and continues to be...
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Full title
HIF1[alpha] is dispensable for oocyte development and female fertility in mice
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TN_cdi_gale_infotracmisc_A708469700
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A708469700
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ISSN
2167-8359
E-ISSN
2167-8359
DOI
10.7717/peerj.13370