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Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate...

Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A744224214

Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate Dehydrogenase Heterozygote Knock Out Animals

About this item

Full title

Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate Dehydrogenase Heterozygote Knock Out Animals

Publisher

MDPI AG

Journal title

Antioxidants, 2022-07, Vol.11 (8)

Language

English

Formats

Publication information

Publisher

MDPI AG

Subjects

More information

Scope and Contents

Contents

α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that has been identified in neurodegenerative diseases such as in Alzheimer's disease. The aim of the present study was to establish the role of the KGDHc and its subunits in the bioenergetics and...

Alternative Titles

Full title

Reverse and Forward Electron Flow-Induced H[sub.2]O[sub.2] Formation Is Decreased in α-Ketoglutarate Dehydrogenase Heterozygote Knock Out Animals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A744224214

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A744224214

Other Identifiers

ISSN

2076-3921

E-ISSN

2076-3921

DOI

10.3390/antiox11081487

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