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Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of n...

Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of n...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A768424930

Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions

About this item

Full title

Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions

Publisher

Oxford University Press

Journal title

Journal of Neuropathology and Experimental Neurology, 2023, Vol.82 (3), p.231

Language

English

Formats

Publication information

Publisher

Oxford University Press

More information

Scope and Contents

Contents

Fused in sarcoma (FUS), coded by FUS, is a heterogeneous nuclear ribonucleoprotein (hnRNP). FUS mutations are among the major mutations in familial amyotrophic lateral sclerosis (ALS-FUS: ALS6). The pathological hallmarks of ALS-FUS are FUS-positive neuronal cytoplasmic inclusions (NCI). We examined various hnRNPs in FUS NCIs in the hippocampus in...

Alternative Titles

Full title

Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A768424930

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A768424930

Other Identifiers

ISSN

0022-3069

DOI

10.1093/jnen/nlac124

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