Oxymatrine protects articular chondrocytes from IL-1[beta]-induced damage through autophagy activati...
Oxymatrine protects articular chondrocytes from IL-1[beta]-induced damage through autophagy activation via AKT/mTOR signaling pathway inhibition
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Author / Creator
Lu, Jinying , Bian, Jiang , Wang, Yutong , Zhao, Yan , Zhao, Xinmin , Wang, Gao and Yang, Jing
Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Contents
Background Osteoarthritis (OA) is a common degenerative joint disease characterized by persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine alkaloid extracted from the traditional Chinese medicine, matrine, and possesses anti-inflammatory properties that may help regulate the pathogenesis of OA; however, its...
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Full title
Oxymatrine protects articular chondrocytes from IL-1[beta]-induced damage through autophagy activation via AKT/mTOR signaling pathway inhibition
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Record Identifier
TN_cdi_gale_infotracmisc_A786183906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A786183906
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ISSN
1749-799X
E-ISSN
1749-799X
DOI
10.1186/s13018-024-04667-2
