The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human b...
The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells
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Publisher
BioMed Central Ltd
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Language
English
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BioMed Central Ltd
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Contents
Triptans are anti-migraine drugs with a potential central site of action. However, it is not known to what extent triptans cross the blood-brain barrier (BBB). The aim of this study was therefore to determine if triptans pass the brain capillary endothelium and investigate the possible underlying mechanisms with focus on the involvement of the puta...
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Full title
The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells
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TN_cdi_gale_infotracmisc_A793113284
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A793113284
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ISSN
2045-8118
E-ISSN
2045-8118
DOI
10.1186/s12987-024-00544-6
