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Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in...

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A793565604

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-IN/I-phenethyl-5-phenylmorphans

About this item

Full title

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-IN/I-phenethyl-5-phenylmorphans

Publisher

MDPI AG

Journal title

Molecules (Basel, Switzerland), 2024-05, Vol.29 (9)

Language

English

Formats

Publication information

Publisher

MDPI AG

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The synthesis of stereochemically pure oximes, amines, saturated and unsaturated cyanomethyl compounds, and methylaminomethyl compounds at the C9 position in 3-hydroxy-N-phenethyl-5-phenylmorphans provided μ-opioid receptor (MOR) agonists with varied efficacy and potency. One of the most interesting compounds, (2-((1S,5R,9R)-5-(3-hydroxyphenyl)-2-p...

Alternative Titles

Full title

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-IN/I-phenethyl-5-phenylmorphans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A793565604

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A793565604

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules29091926

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