A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-target...
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome
About this item
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Publisher
BioMed Central Ltd
Journal title
Language
English
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Publisher
BioMed Central Ltd
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Scope and Contents
Contents
G-quadruplex DNA (G4) is a non-canonical structure forming in guanine-rich regions, which play a vital role in cancer biology and are now being acknowledged in both nuclear and mitochondrial (mt) genome. However, the impact of G4-based targeted therapy on both nuclear and mt genome, affecting mt function and its underlying mechanisms remain largely...
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Full title
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome
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TN_cdi_gale_infotracmisc_A793711362
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A793711362
Other Identifiers
ISSN
1021-7770
DOI
10.1186/s12929-024-01041-6
