Mitochondria regulate proliferation in adult cardiac myocytes
Mitochondria regulate proliferation in adult cardiac myocytes
About this item
Full title
Author / Creator
Waypa, Gregory B , Smith, Kimberly A , Mungai, Paul T , Dudley, Vincent J , Helmin, Kathryn A , Singer, Benjamin D , Peek, Clara Bien , Bass, Joseph , Nelson, Lauren , Shah, Sanjiv J , Ofman, Gaston , Wasserstrom, J. Andrew , Muller, William A , Misharin, Alexander V , Budinger, G.R. Scott , Abdala-Valencia, Hiam , Chandel, Navdeep S , Dokic, Danijela , Bartom, Elizabeth , Zhang, Shuang , Tatekoshi, Yuki , Mahmoodzadeh, Amir , Ardehali, Hossein , Thorp, Edward B and Schumacker, Paul T
Publisher
American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back to a fetal glycolytic phenotype would restore proliferative capacity. We deleted Uqcrfsl (mitochondrial Rieske iron- s...
Alternative Titles
Full title
Mitochondria regulate proliferation in adult cardiac myocytes
Authors, Artists and Contributors
Author / Creator
Smith, Kimberly A
Mungai, Paul T
Dudley, Vincent J
Helmin, Kathryn A
Singer, Benjamin D
Peek, Clara Bien
Bass, Joseph
Nelson, Lauren
Shah, Sanjiv J
Ofman, Gaston
Wasserstrom, J. Andrew
Muller, William A
Misharin, Alexander V
Budinger, G.R. Scott
Abdala-Valencia, Hiam
Chandel, Navdeep S
Dokic, Danijela
Bartom, Elizabeth
Zhang, Shuang
Tatekoshi, Yuki
Mahmoodzadeh, Amir
Ardehali, Hossein
Thorp, Edward B
Schumacker, Paul T
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A803497467
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A803497467
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI165482.
