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Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alz...

Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alz...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A814519153

Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice

About this item

Full title

Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice

Publisher

BioMed Central Ltd

Journal title

Journal of Neuroinflammation, 2024, Vol.21 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

The Interleukin-6 (IL-6)-signal transducer and activator of transcription 3 (STAT3) pathway, along with the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, are critical contributors to neuroinflammation in Alzheimer's disease (AD). Although previous research outside the context of AD has indicated that the IL-6-STAT3...

Alternative Titles

Full title

Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A814519153

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A814519153

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-024-03277-3

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