Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alz...
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice
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Author / Creator
Liu, Min , Pan, Jirong , Li, Xiaomeng , Zhang, Xueling , Tian, Fan , Li, Mingfeng , Wu, Xinghan , Zhang, Ling and Qin, Chuan
Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Contents
The Interleukin-6 (IL-6)-signal transducer and activator of transcription 3 (STAT3) pathway, along with the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, are critical contributors to neuroinflammation in Alzheimer's disease (AD). Although previous research outside the context of AD has indicated that the IL-6-STAT3...
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Full title
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice
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Record Identifier
TN_cdi_gale_infotracmisc_A814519153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A814519153
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-024-03277-3