Validation of the γH2AX biomarker for genotoxicity assessment: a review
Validation of the γH2AX biomarker for genotoxicity assessment: a review
About this item
Full title
Author / Creator
Kopp, B. , Khoury, L. and Audebert, Marc
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
The H2AX histone protein is rapidly phosphorylated at the serine-139 position (γH2AX) in response to a broad range of DNA lesions. γH2AX induction is one of the earliest events in the DNA damage response (DDR) and plays a central role in sensing and repairing DNA damage. Since its discovery, measuring γH2AX formation using numerous methods in in vi...
Alternative Titles
Full title
Validation of the γH2AX biomarker for genotoxicity assessment: a review
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_anses_02349053v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_anses_02349053v1
Other Identifiers
ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-019-02511-9
