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Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and P...

Study on the Putative Contribution of Caspases and the ...

Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00170857v1

Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2

About this item

Full title

Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Neuro-degenerative diseases, 2007-01, Vol.4 (2-3), p.156-163

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

The presenilin-dependent γ-secretase complex is mainly composed of four distinct proteins, namely presenilin 1 or presenilin 2, nicastrin, anterior pharynx defective-1 (Aph-1) and presenilin enhancer (Pen-2). The mechanisms by which the complex is assembled, how its stochiometry is controlled and how its catalytic activity is regulated are poorly u...

Alternative Titles

Full title

Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00170857v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00170857v1

Other Identifiers

ISBN

3805583397,9783805583398

ISSN

1660-2854

E-ISSN

1660-2862

DOI

10.1159/000101840

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