Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression
Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Single-unit recordings and optogenetic manipulations in mice undergoing auditory fear conditioning show that fear expression is related to the phasic inhibition of prefrontal cortex (PFC) parvalbumin interneurons; inhibition disinhibits PFC projection neurons and synchronizes their firing, leading to fear expression.
Control of fear-related beha...
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Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression
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TN_cdi_hal_primary_oai_HAL_hal_01155132v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01155132v1
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12755
