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Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01538351v1

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

About this item

Full title

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2013-02, Vol.494 (7435), p.111-115

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The livers of obese mice and humans show increased levels of miR-802 resulting in impaired glucose tolerance and decreased insulin sensitivity through silencing of
Hnf1b
, revealing a novel pathway with potential relevance for type 2 diabetes.
A microRNA linked to glucose metabolism
Regulation of gene expression by microRNAs is known to...

Alternative Titles

Full title

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_01538351v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01538351v1

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature11793

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