Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The livers of obese mice and humans show increased levels of miR-802 resulting in impaired glucose tolerance and decreased insulin sensitivity through silencing of
Hnf1b
, revealing a novel pathway with potential relevance for type 2 diabetes.
A microRNA linked to glucose metabolism
Regulation of gene expression by microRNAs is known to...
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Full title
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
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TN_cdi_hal_primary_oai_HAL_hal_01538351v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01538351v1
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11793