ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosom...
ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
About this item
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Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
Summary
Although phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, little is known about their mechanism of action. Localized in the outer membrane of mycobacterial pathogens, DIM are predicted to interact with host cell membranes. Interaction with eukary...
Alternative Titles
Full title
ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_02326055v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02326055v1
Other Identifiers
ISSN
1462-5814
E-ISSN
1462-5822
DOI
10.1111/cmi.12726
