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ArticlesPeer ReviewedFull Text
ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
Author / Creator:Augenstreich, Jacques ; Arbues, Ainhoa ; Simeone, Roxane ; Haanappel, Evert ; Wegener, Alice ; Sayes, Fadel ; Le Chevalier, Fabien ; Chalut, Christian ; Malaga, Wladimir ; Guilhot, Christophe ; Brosch, Roland ; Astarie‐Dequeker, Catherine
Publisher:England: John Wiley & Sons, Inc
Journal title:Cellular microbiology, 2017-07, Vol.19 (7), p.e12726-n/a
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Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
Author / Creator:Gonzalo-Asensio, Jesús ; Malaga, Wladimir ; Pawlik, Alexandre ; Astarie-Dequeker, Catherine ; Passemar, Charlotte ; Moreau, Flavie ; Laval, Françoise ; Daffé, Mamadou ; Martin, Carlos ; Brosch, Roland ; Guilhot, Christophe
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.11491-11496
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli
Author / Creator:Malaga, Wladimir ; Payros, Delphine ; Meunier, Eva ; Frigui, Wafa ; Sayes, Fadel ; Pawlik, Alexandre ; Orgeur, Mickael ; Berrone, Céline ; Moreau, Flavie ; Mazères, Serge ; Gonzalo-Asensio, Jesus ; Rengel, David ; Martin, Carlos ; Astarie-Dequeker, Catherine ; Mourey, Lionel ; Brosch, Roland ; Guilhot, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-07, Vol.19 (7), p.e1011437-e1011437
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Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host–pathogen interactions
Author / Creator:Passemar, Charlotte ; Arbués, Ainhoa ; Malaga, Wladimir ; Mercier, Ingrid ; Moreau, Flavie ; Lepourry, Laurence ; Neyrolles, Olivier ; Guilhot, Christophe ; Astarie‐Dequeker, Catherine
Publisher:England: John Wiley & Sons, Inc
Journal title:Cellular microbiology, 2014-02, Vol.16 (2), p.195-213
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ArticlesPeer ReviewedFull Text
Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids
Author / Creator:Astarie-Dequeker, Catherine ; Le Guyader, Laurent ; Malaga, Wladimir ; Seaphanh, Fam-Ky ; Chalut, Christian ; Lopez, André ; Guilhot, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2009-02, Vol.5 (2), p.e1000289-e1000289
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Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages
Author / Creator:Payros, Delphine ; Alonso, Henar ; Malaga, Wladimir ; Volle, Arnaud ; Mazères, Serge ; Déjean, Sébastien ; Valière, Sophie ; Moreau, Flavie ; Balor, Stéphanie ; Stella, Alexandre ; Combes-Soia, Lucie ; Burlet-Schiltz, Odile ; Bouchez, Olivier ; Nigou, Jérôme ; Astarie-Dequeker, Catherine ; Guilhot, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2021-11, Vol.17 (11), p.e1010020-e1010020
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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages
Author / Creator:Bah, Aïcha ; Sanicas, Merlin ; Nigou, Jérôme ; Guilhot, Christophe ; Astarie-Dequeker, Catherine ; Vergne, Isabelle
Publisher:Switzerland: MDPI
Journal title:Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.666
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Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli
Author / Creator:Allen, Aideen C. ; Malaga, Wladimir ; Gaudin, Cyril ; Volle, Arnaud ; Moreau, Flavie ; Hassan, Ali ; Astarie-Dequeker, Catherine ; Peixoto, Antonio ; Antoine, Rudy ; Pawlik, Alexandre ; Frigui, Wafa ; Berrone, Céline ; Brosch, Roland ; Supply, Philip ; Guilhot, Christophe
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2021-08, Vol.6 (8), p.1082-1093
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ArticlesPeer ReviewedFull Text
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
Author / Creator:Delettre, Cécile ; Lenaers, Guy ; Griffoin, Jean-Michel ; Gigarel, Nadine ; Lorenzo, Corinne ; Belenguer, Pascale ; Pelloquin, Laetitia ; Grosgeorge, Josiane ; Turc-Carel, Claude ; Perret, Eric ; Astarie-Dequeker, Catherine ; Lasquellec, Laetitia ; Arnaud, Bernard ; Ducommun, Bernard ; Kaplan, Josseline ; Hamel, Christian P.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2000-10, Vol.26 (2), p.207-210
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ArticlesPeer ReviewedFull Text
Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes
Author / Creator:Tabouret, Guillaume ; Astarie-Dequeker, Catherine ; Demangel, Caroline ; Malaga, Wladimir ; Constant, Patricia ; Ray, Aurélie ; Honoré, Nadine ; Bello, Nana Fatimath ; Perez, Esther ; Daffé, Mamadou ; Guilhot, Christophe
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2010-10, Vol.6 (10), p.e1001159-e1001159
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ArticlesPeer ReviewedFull Text
The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages
Author / Creator:Augenstreich, Jacques ; Haanappel, Evert ; Ferré, Guillaume ; Czaplicki, Georges ; Jolibois, Franck ; Destainville, Nicolas ; Guilhot, Christophe ; Milon, Alain ; Astarie-Dequeker, Catherine ; Chavent, Matthieu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (51), p.25649-25658
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ArticlesPeer ReviewedFull Text
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macr...
Author / Creator:Delphine Payros ; Henar Alonso ; Wladimir Malaga ; Arnaud Volle ; Serge Mazères ; Sébastien Déjean ; Sophie Valière ; Flavie Moreau ; Stéphanie Balor ; Alexandre Stella ; Lucie Combes-Soia ; Odile Burlet-Schiltz ; Olivier Bouchez ; Jérôme Nigou ; Catherine Astarie-Dequeker ; Christophe Guilhot
Publisher:Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2021-11, Vol.17 (11)
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ArticlesPeer ReviewedFull Text
Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions: Functional overlap between...
Author / Creator:Passemar, Charlotte ; Arbués, Ainhoa ; Malaga, Wladimir ; Mercier, Ingrid ; Moreau, Flavie ; Lepourry, Laurence ; Neyrolles, Olivier ; Guilhot, Christophe ; Astarie-Dequeker, Catherine
Journal title:Cellular microbiology, 2014-02, Vol.16 (2), p.195-213
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ArticlesPeer ReviewedFull Text
Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes: e1001159
Author / Creator:Tabouret, Guillaume ; Astarie-Dequeker, Catherine ; Demangel, Caroline ; Malaga, Wladimir ; Constant, Patricia ; Ray, Aurélie ; Honoré, Nadine ; Bello, Nana Fatimath ; Perez, Esther ; Daffé, Mamadou ; Guilhot, Christophe
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2010-10, Vol.6 (10)
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ArticlesPeer ReviewedFull Text
Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids: e1000289
Author / Creator:Astarie-Dequeker, Catherine ; Guyader, Laurent Le ; Malaga, Wladimir ; Seaphanh, Fam-Ky ; Chalut, Christian ; Lopez, André ; Guilhot, Christophe
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2009-02, Vol.5 (2)
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ArticlesFull Text
Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors
Author / Creator:Augenstreich, Jacques ; Haanappel, Evert ; Fadel Sayes ; Simeone, Roxane ; Guillet, Valerie ; Mazeres, Serge ; Chalut, Christian ; Mourey, Lionel ; Brosch, Roland ; Guilhot, Christophe ; Astarie-Dequeker, Catherine
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-05
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ArticlesFull Text
The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages
Author / Creator:Augenstreich, Jacques ; Haanappel, Evert ; Ferré, Guillaume ; Czaplicki, George ; Jolibois, Franck ; Destainville, Nicolas ; Guilhot, Christophe ; Milon, Alain ; Astarie-Dequeker, Catherine ; Chavent, Matthieu
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-06
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ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis

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Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli

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Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host–pathogen interactions

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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

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Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages

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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

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Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

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Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

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Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes

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The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

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Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macr...

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Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions: Functional overlap between...

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Mycobacterium leprae Phenolglycolipid-1 Expressed by Engineered M. bovis BCG Modulates Early Interaction with Human Phagocytes: e1001159

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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids: e1000289

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Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors

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The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

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