Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, rand...
Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study
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Author / Creator
European Huntington's Disease Network , Huntington Study Group investigators , Reilmann, Ralf , Grachev, Igor D , Savola, Juha-Matti , Borowsky, Beth , Eyal, Eli , Gross, Nicholas , Langbehn, Douglas , Schubert, Robin , Wickenberg, Anna Teige , Papapetropoulos, Spyros , Squitieri, Ferdinando , Kieburtz, Karl , Landwehrmeyer, G Bernhard , Agarwal, Pinky , Anderson, Karen E , Aziz, Nasir A , Azulay, Jean-Phillippe , Bachoud-Levi, Anne C , Barker, Roger , Bebak, Agnieszka , Beuth, Markus , Biglan, Kevin , Blin, Stephanie , Bonelli, Raphael , Caldwell, Sue , Calvas, Fabienne , Carlos, Jonielyn , Chong, Terrence , Chua, Phyllis , Coleman, Allison , Corey-Bloom, Jody , Cousins, Rebecca , Craufurd, David , De Michele, Giuseppe , Dornhege, Laura , Feigin, Andrew , Gallehawk, Stephanie , Gauteul, Pascale , Gonzales, Carey , Griffith, Jane , Guttman, Mark , Heim, Beatrix , Heller, Hope , Hjermind, Lena , Ivanko, Larry , Jaynes, Jessica , Jenckes, Mollie , Kaminski, Barbara , Kampstra, Anne , Konkel, Agnieszka , Kopishinskaya, Svetlana , Krystkowiak, Pierre , Komati, Suresh K , Lakoning, Stefan , Latipova, Guzal , Leavitt, Blair , Loy, Clement , Madsen, Louise , Marder, Karen , Mason, Sarah , Mendis, Neila , Mendis, Tilak , Norris, Virginia , Olivier, Audrey , Orth, Michael , Owens, Ashley , Panegyres, Peter , Perlman, Susan , Preston, Joy , Puch, Alicja , Rialland, Amandine , Rickards, Hugh , Romoli, Anna M , Ross, Christopher , Rosser, Anne , Rudzinska, Monika , Russo, Cinzina V , Saft, Carsten , Segro, Victoria , Seppi, Klaus , Shannon, Barbara , Shprecher, David , Simonin, Clemence , Skitt, Zara , Soliveri, Paola , Squitieri, Ferdinando , Suski, Valarie , Stepniak, Iwona , Sungmee, Park , Temirbaeva, Sofia , Uhl, Stefanie , Vangsted-Hansen, Christina , Verny, Christophe , Wall, Paola , Walker, Francis , Wasserman, Paula , Witkowski, Grzegorz , Wright, Jan , Zalyalova, Zuleykha and Zielonka, Daniel
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Previous trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The aim of this study was to ascertain whether higher doses of pridopidine than previously tested reduce motor symptoms in a dose-dependent manner while maintaining acceptable safety and tolerability.
PRIDE-HD was a randomised, placeb...
Alternative Titles
Full title
Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study
Authors, Artists and Contributors
Author / Creator
Huntington Study Group investigators
Reilmann, Ralf
Grachev, Igor D
Savola, Juha-Matti
Borowsky, Beth
Eyal, Eli
Gross, Nicholas
Langbehn, Douglas
Schubert, Robin
Wickenberg, Anna Teige
Papapetropoulos, Spyros
Squitieri, Ferdinando
Kieburtz, Karl
Landwehrmeyer, G Bernhard
Agarwal, Pinky
Anderson, Karen E
Aziz, Nasir A
Azulay, Jean-Phillippe
Bachoud-Levi, Anne C
Barker, Roger
Bebak, Agnieszka
Beuth, Markus
Biglan, Kevin
Blin, Stephanie
Bonelli, Raphael
Caldwell, Sue
Calvas, Fabienne
Carlos, Jonielyn
Chong, Terrence
Chua, Phyllis
Coleman, Allison
Corey-Bloom, Jody
Cousins, Rebecca
Craufurd, David
De Michele, Giuseppe
Dornhege, Laura
Feigin, Andrew
Gallehawk, Stephanie
Gauteul, Pascale
Gonzales, Carey
Griffith, Jane
Guttman, Mark
Heim, Beatrix
Heller, Hope
Hjermind, Lena
Ivanko, Larry
Jaynes, Jessica
Jenckes, Mollie
Kaminski, Barbara
Kampstra, Anne
Konkel, Agnieszka
Kopishinskaya, Svetlana
Krystkowiak, Pierre
Komati, Suresh K
Lakoning, Stefan
Latipova, Guzal
Leavitt, Blair
Loy, Clement
Madsen, Louise
Marder, Karen
Mason, Sarah
Mendis, Neila
Mendis, Tilak
Norris, Virginia
Olivier, Audrey
Orth, Michael
Owens, Ashley
Panegyres, Peter
Perlman, Susan
Preston, Joy
Puch, Alicja
Rialland, Amandine
Rickards, Hugh
Romoli, Anna M
Ross, Christopher
Rosser, Anne
Rudzinska, Monika
Russo, Cinzina V
Saft, Carsten
Segro, Victoria
Seppi, Klaus
Shannon, Barbara
Shprecher, David
Simonin, Clemence
Skitt, Zara
Soliveri, Paola
Squitieri, Ferdinando
Suski, Valarie
Stepniak, Iwona
Sungmee, Park
Temirbaeva, Sofia
Uhl, Stefanie
Vangsted-Hansen, Christina
Verny, Christophe
Wall, Paola
Walker, Francis
Wasserman, Paula
Witkowski, Grzegorz
Wright, Jan
Zalyalova, Zuleykha
Zielonka, Daniel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_02616940v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02616940v1
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(18)30391-0
