UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendriti...
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
About this item
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Author / Creator
Maschalidi, Sophia , Nunes-Hasler, Paula , Nascimento, Clarissa R , Sallent, Ignacio , Lannoy, Valérie , Garfa-Traore, Meriem , Cagnard, Nicolas , Sepulveda, Fernando E , Vargas, Pablo , Lennon-Duménil, Ana-Maria , van Endert, Peter , Capiod, Thierry , Demaurex, Nicolas , Darrasse-Jèze, Guillaume and Manoury, Bénédicte
Publisher
Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Dendritic cells (DC) have the unique ability to present exogenous antigens via the major histocompatibility complex class I pathway to stimulate naive CD8 + T cells. In DCs with a non-functional mutation in Unc93b1 (3d mutation), endosomal acidification, phagosomal maturation, antigen degradation, antigen export to the cytosol and the function of t...
Alternative Titles
Full title
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03103691v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03103691v1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01601-5
