The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidne...
The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Organs and cells must adapt to shear stress induced by biological fluids, but how fluid flow contributes to the execution of specific cell programs is poorly understood. Here we show that shear stress favours mitochondrial biogenesis and metabolic reprogramming to ensure energy production and cellular adaptation in kidney epithelial cells. Shear st...
Alternative Titles
Full title
The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03452662v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03452662v1
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-0566-0
