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Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surfa...

Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surfa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03453132v1

Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

About this item

Full title

Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

Publisher

Nature Publishing Group [1987-....]

Journal title

Oncogene, 2021-05, Vol.40 (23), p.4019-4032

Language

English

Formats

Publication information

Publisher

Nature Publishing Group [1987-....]

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Membrane Type 1 Matrix Metalloprotease (MT1-MMP) contributes to the invasive progression of breast cancers by degrading extracellular matrix tissues. Nucleoside diphosphate kinase, NME1/NM23-H1, has been identified as a metastasis suppressor; however, its contribution to local invasion in breast cancer is not known. Here, we report that NME1 is upr...

Alternative Titles

Full title

Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03453132v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03453132v1

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-021-01826-1

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