Structural basis for the inhibition of the eukaryotic ribosome
Structural basis for the inhibition of the eukaryotic ribosome
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The ribosome is a molecular machine responsible for protein synthesis and a major target for small-molecule inhibitors. Compared to the wealth of structural information available on ribosome-targeting antibiotics in bacteria, our understanding of the binding mode of ribosome inhibitors in eukaryotes is currently limited. Here we used X-ray crystall...
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Full title
Structural basis for the inhibition of the eukaryotic ribosome
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TN_cdi_hal_primary_oai_HAL_hal_03661154v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03661154v1
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13737
