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Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose...

Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03704634v1

Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose metabolism

About this item

Full title

Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose metabolism

Publisher

Frankfurt: EMBO Press

Journal title

EMBO molecular medicine, 2019-06, Vol.11 (6)

Language

English

Formats

Publication information

Publisher

Frankfurt: EMBO Press

More information

Scope and Contents

Contents

Microglia adopt numerous fates with homeostatic microglia (HM) and a microglial neurodegenerative phenotype (MGnD) representing two opposite ends. A number of variants in genes selectively expressed in microglia are associated with an increased risk for neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal lobar degeneratio...

Alternative Titles

Full title

Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03704634v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03704634v1

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201809711

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