A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
About this item
Full title
Author / Creator
Francque, Sven M , Bedossa, Pierre , Ratziu, Vlad , Anstee, Quentin M , Bugianesi, Elisabetta , Sanyal, Arun J , Loomba, Rohit , Harrison, Stephen A , Balabanska, Rozalina , Mateva, Lyudmila , Lanthier, Nicolas , Alkhouri, Naim , Moreno, Christophe , Schattenberg, Jörn M , Stefanova-Petrova, Diana , Vonghia, Luisa , Rouzier, Régine , Guillaume, Maeva , Hodge, Alexander , Romero-Gómez, Manuel , Huot-Marchand, Philippe , Baudin, Martine , Richard, Marie-Paule , Abitbol, Jean-Louis , Broqua, Pierre , Junien, Jean-Louis , Abdelmalek, Manal F and NATIVE Study Group
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Lanifibranor is a pan–peroxisome proliferator–activated receptor agonist that modulates metabolic and inflammatory pathways. In this 24-week, phase 2b, placebo-controlled trial involving patients with NASH, 1200 mg of lanifibranor, but not 800 mg, significantly improved histologic features of NASH. Weight gain, anemia, peripheral edema, diarrhea, a...
Alternative Titles
Full title
A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH
Authors, Artists and Contributors
Author / Creator
Bedossa, Pierre
Ratziu, Vlad
Anstee, Quentin M
Bugianesi, Elisabetta
Sanyal, Arun J
Loomba, Rohit
Harrison, Stephen A
Balabanska, Rozalina
Mateva, Lyudmila
Lanthier, Nicolas
Alkhouri, Naim
Moreno, Christophe
Schattenberg, Jörn M
Stefanova-Petrova, Diana
Vonghia, Luisa
Rouzier, Régine
Guillaume, Maeva
Hodge, Alexander
Romero-Gómez, Manuel
Huot-Marchand, Philippe
Baudin, Martine
Richard, Marie-Paule
Abitbol, Jean-Louis
Broqua, Pierre
Junien, Jean-Louis
Abdelmalek, Manal F
NATIVE Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03732372v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03732372v1
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2036205
