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E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial nec...

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial nec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04013948v1

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis

About this item

Full title

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2021-07, Vol.23 (7), p.796-807

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Inflammatory bowel diseases present with elevated levels of intestinal epithelial cell (IEC) death, which compromises the gut barrier, activating immune cells and triggering more IEC death. The endogenous signals that prevent IEC death and break this vicious cycle, allowing resolution of intestinal inflammation, remain largely unknown. Here we show...

Alternative Titles

Full title

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04013948v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04013948v1

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-021-00708-8

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