Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
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Author / Creator
Bruchard, Mélanie , Geindreau, Mannon , Perrichet, Anaïs , Truntzer, Caroline , Ballot, Elise , Boidot, Romain , Racoeur, Cindy , Barsac, Emilie , Chalmin, Fanny , Hibos, Christophe , Baranek, Thomas , Paget, Christophe , Ryffel, Bernhard , Rébé, Cédric , Paul, Catherine , Végran, Frédérique and Ghiringhelli, François
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Tumors poorly infiltrated by T cells are more resistant to immunogenic chemotherapies and checkpoint inhibition than highly infiltrated tumors. Using murine models, we found that CCR6
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type 3 innate lymphoid cells (ILC3s) can trigger an increase in the number of T cells infiltrating a tumor. Shortly after administration of cisplatin chemothe...
Alternative Titles
Full title
Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
Authors, Artists and Contributors
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04268845v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04268845v1
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01120-y
