Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia
Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia
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Author / Creator
Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation , Peffault de Latour, Régis , Kulasekararaj, Austin , Iacobelli, Simona , Terwel, Sofie R , Cook, Riley , Griffin, Morag , Halkes, Constantijn J.M , Recher, Christian , Barraco, Fiorenza , Forcade, Edouard , Vallejo, Juan-Carlos , Drexler, Beatrice , Mear, Jean-Baptiste , Smith, Alexander E , Angelucci, Emanuele , Raymakers, Reinier A.P , de Groot, Marco R , Daguindau, Etienne , Nur, Erfan , Barcellini, Wilma , Russell, Nigel H , Terriou, Louis , Iori, Anna-Paola , La Rocca, Ursula , Sureda, Anna , Sánchez-Ortega, Isabel , Xicoy, Blanca , Jarque, Isidro , Cavenagh, James , Sicre de Fontbrune, Flore , Marotta, Serena , Munir, Talha , Tjon, Jennifer M.L , Tavitian, Suzanne , Praire, Aline , Clement, Laurence , Rabian, Florence , Marano, Luana , Hill, Anita , Palmisani, Elena , Muus, Petra , Cacace, Fabiana , Frieri, Camilla , van Lint, Maria-Teresa , Passweg, Jakob R , Marsh, Judith C.W , Socié, Gérard , Mufti, Ghulam J , Dufour, Carlo and Risitano, Antonio M
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A randomized trial comparing immunosuppression (horse ATG and cyclosporine) with the same therapy plus eltrombopag showed more rapid and complete responses with the addition of eltrombopag. Severe adverse effects were similar in the two groups. Somatic mutations increased in both groups but did not lead to an increase in leukemia.
Alternative Titles
Full title
Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia
Authors, Artists and Contributors
Author / Creator
Peffault de Latour, Régis
Kulasekararaj, Austin
Iacobelli, Simona
Terwel, Sofie R
Cook, Riley
Griffin, Morag
Halkes, Constantijn J.M
Recher, Christian
Barraco, Fiorenza
Forcade, Edouard
Vallejo, Juan-Carlos
Drexler, Beatrice
Mear, Jean-Baptiste
Smith, Alexander E
Angelucci, Emanuele
Raymakers, Reinier A.P
de Groot, Marco R
Daguindau, Etienne
Nur, Erfan
Barcellini, Wilma
Russell, Nigel H
Terriou, Louis
Iori, Anna-Paola
La Rocca, Ursula
Sureda, Anna
Sánchez-Ortega, Isabel
Xicoy, Blanca
Jarque, Isidro
Cavenagh, James
Sicre de Fontbrune, Flore
Marotta, Serena
Munir, Talha
Tjon, Jennifer M.L
Tavitian, Suzanne
Praire, Aline
Clement, Laurence
Rabian, Florence
Marano, Luana
Hill, Anita
Palmisani, Elena
Muus, Petra
Cacace, Fabiana
Frieri, Camilla
van Lint, Maria-Teresa
Passweg, Jakob R
Marsh, Judith C.W
Socié, Gérard
Mufti, Ghulam J
Dufour, Carlo
Risitano, Antonio M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04526478v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04526478v1
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2109965
