Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their...
Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli
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Author / Creator
Dallmann-Sauer, Monica , Fava, Vinicius M , Malherbe, Stephanus T , MacDonald, Candice E , Orlova, Marianna , Kroon, Elouise E , Cobat, Aurélie , Boisson-Dupuis, Stéphanie , Hoal, Eileen G , Abel, Laurent , Möller, Marlo , Casanova, Jean-Laurent , Walzl, Gerhard , Du Plessis, Nelita and Schurr, Erwin
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Natural resistance to Mycobacterium tuberculosis (Mtb) infection in some people with HIV (PWH) is unexplained. We performed single cell RNA-sequencing of bronchoalveolar lavage cells, unstimulated or ex vivo stimulated with Mtb, for 7 PWH who were TST & IGRA positive (called LTBI) and 6 who were persistently TST & IGRA negative (called resisters)....
Alternative Titles
Full title
Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli
Authors, Artists and Contributors
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_04934001v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04934001v1
Other Identifiers
ISSN
1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI188016
