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Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes

Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04981971v1

Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes

About this item

Full title

Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2020-06, Vol.17 (6), p.615-620

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for samples containing a mixture of genotypes, whether they are natural or experimentally combined. Multiplexing across donors is a popular experimental design that can avoid batch effects, reduce costs and improve doublet detection. By using variants detected in scRNA-...

Alternative Titles

Full title

Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_04981971v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04981971v1

Other Identifiers

ISSN

1548-7091,1548-7105

E-ISSN

1548-7105

DOI

10.1038/s41592-020-0820-1

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