Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes
Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for samples containing a mixture of genotypes, whether they are natural or experimentally combined. Multiplexing across donors is a popular experimental design that can avoid batch effects, reduce costs and improve doublet detection. By using variants detected in scRNA-...
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Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes
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TN_cdi_hal_primary_oai_HAL_hal_04981971v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_04981971v1
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ISSN
1548-7091,1548-7105
E-ISSN
1548-7105
DOI
10.1038/s41592-020-0820-1