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The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages...

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_05034381v1

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory

About this item

Full title

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2015-10, Vol.16 (10), p.1034-1043

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The role of the stress-induced transcription factor ATF7 in immunity is largely unknown. Ishii and colleagues show that ATF7 represses select innate immunity–related genes, but activity is downregulated during the induction of macrophage memory.
Immunological memory is thought to be mediated exclusively by lymphocytes. However, enhanced innate i...

Alternative Titles

Full title

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_05034381v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_05034381v1

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3257

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