A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T c...
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The molecular mechanisms directing the development of 'natural' CD4
+
CD25
+
Foxp3
+
regulatory T cells (T
reg
cells) in the thymus are not thoroughly understood. We show here that conditional deletion of transforming growth factor-β receptor I (TβRI) in T cells blocked the appearance of CD4
+
CD25
+
Foxp3
+
Alternative Titles
Full title
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_00484154v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_00484154v1
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1607
