Visualization of chemical modifications in the human 80S ribosome structure
Visualization of chemical modifications in the human 80S ribosome structure
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chemical modifications of human ribosomal RNA (rRNA) are introduced during biogenesis and have been implicated in the dysregulation of protein synthesis, as is found in cancer and other diseases. However, their role in this phenomenon is unknown. Here we visualize more than 130 individual rRNA modifications in the three-dimensional structure of the...
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Full title
Visualization of chemical modifications in the human 80S ribosome structure
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TN_cdi_hal_primary_oai_HAL_inserm_02409680v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02409680v1
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature24482
