A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K2...
A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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We quantified genome-wide patterns of lysine H3K27 acetylation (H3K27ac) in entorhinal cortex samples from Alzheimer’s disease (AD) cases and matched controls using chromatin immunoprecipitation and highly parallel sequencing. We observed widespread acetylomic variation associated with AD neuropathology, identifying 4,162 differential peaks (false...
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A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex
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TN_cdi_hal_primary_oai_HAL_inserm_02457765v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02457765v1
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1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-018-0253-7