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Engineered niches support the development of human dendritic cells in humanized mice

Engineered niches support the development of human dendritic cells in humanized mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02633642v1

Engineered niches support the development of human dendritic cells in humanized mice

About this item

Full title

Engineered niches support the development of human dendritic cells in humanized mice

Publisher

Nature Publishing Group

Journal title

Nature communications, 2020-04, Vol.11 (1)

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive immunity. Modeling cDC development is crucial to study cDCs and harness their therapeutic potential. Here we address whether cDCs could differentiate in response to trophic cues delivered by mesenchymal components of the hematopoietic niche. We find t...

Alternative Titles

Full title

Engineered niches support the development of human dendritic cells in humanized mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_inserm_02633642v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02633642v1

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15937-y

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