Engineered niches support the development of human dendritic cells in humanized mice
Engineered niches support the development of human dendritic cells in humanized mice
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Nature Publishing Group
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English
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Nature Publishing Group
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Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive immunity. Modeling cDC development is crucial to study cDCs and harness their therapeutic potential. Here we address whether cDCs could differentiate in response to trophic cues delivered by mesenchymal components of the hematopoietic niche. We find t...
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Engineered niches support the development of human dendritic cells in humanized mice
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TN_cdi_hal_primary_oai_HAL_inserm_02633642v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02633642v1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15937-y