Engineered niches support the development of human dendritic cells in humanized mice
Engineered niches support the development of human dendritic cells in humanized mice
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Publisher
Nature Publishing Group
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Language
English
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Nature Publishing Group
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Contents
Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive immunity. Modeling cDC development is crucial to study cDCs and harness their therapeutic potential. Here we address whether cDCs could differentiate in response to trophic cues delivered by mesenchymal components of the hematopoietic niche. We find t...
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Full title
Engineered niches support the development of human dendritic cells in humanized mice
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TN_cdi_hal_primary_oai_HAL_inserm_02633642v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_02633642v1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15937-y
