Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The nicotinic acetylcholine receptors (nAChRs) are the most well understood membrane receptors for neurotransmitters at the structural and functional level. They are integral allosteric membrane proteins comprising five identical or homologous subunits symmetrically arranged around a central ionic channel.
The acetylcholine (ACh)-b...
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Full title
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
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TN_cdi_hal_primary_oai_HAL_pasteur_02542745v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_pasteur_02542745v1
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd2927
