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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23769019

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

About this item

Full title

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (4), p.1235-1235

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cancer cells reprogram their metabolism for optimal growth and survival. AMPK-activated protein kinase (AMPK) is a key energy sensor that controls many metabolic pathways including metabolic reprogramming. However, its role in cancer is poorly understood. Some studies claim that it has a tumor suppressor role while others show its protumor role. Tw...

Alternative Titles

Full title

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_23769019

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23769019

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1311121111

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