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Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condens...

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condens...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772702

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

About this item

Full title

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (19), p.6940-6945

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The efforts to grow mechanically functional cartilage from human mesenchymal stem cells have not been successful. We report that clinically sized pieces of human cartilage with physiologic stratification and biomechanics can be grown in vitro by recapitulating some aspects of the developmental process of mesenchymal condensation. By exposure to tra...

Alternative Titles

Full title

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_23772702

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772702

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1324050111

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