Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condens...
Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The efforts to grow mechanically functional cartilage from human mesenchymal stem cells have not been successful. We report that clinically sized pieces of human cartilage with physiologic stratification and biomechanics can be grown in vitro by recapitulating some aspects of the developmental process of mesenchymal condensation. By exposure to tra...
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Full title
Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation
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Record Identifier
TN_cdi_jstor_primary_23772702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_23772702
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1324050111