Maternal Nanos Represses hid/skl-Dependent Apoptosis to Maintain the Germ Line in Drosophila Embryos
Maternal Nanos Represses hid/skl-Dependent Apoptosis to Maintain the Germ Line in Drosophila Embryos
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Nanos (Nos) is an evolutionary conserved protein essential for the survival of primordial germ cells. In Drosophila, maternal Nos partitions into pole cells and suppresses apoptosis to permit proper germ-line development. However, how this critical event is regulated by Nos has remained elusive. Here, we report that Nos represses apoptosis of pole...
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Full title
Maternal Nanos Represses hid/skl-Dependent Apoptosis to Maintain the Germ Line in Drosophila Embryos
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TN_cdi_jstor_primary_25427508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25427508
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0610052104
