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Inhibition of VEGF-A Prevents the Angiogenic Switch and Results in Increased Survival of$Apc^{+/\tex...

Inhibition of VEGF-A Prevents the Angiogenic Switch and Results in Increased Survival of$Apc^{+/\tex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25435983

Inhibition of VEGF-A Prevents the Angiogenic Switch and Results in Increased Survival of$Apc^{+/\text{min}}$Mice

About this item

Full title

Inhibition of VEGF-A Prevents the Angiogenic Switch and Results in Increased Survival of$Apc^{+/\text{min}}$Mice

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (25), p.10625-10630

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

Anti-VEGF-A monoclonal antibodies, in combination with chemotherapy, result in a survival benefit in patients with metastatic colorectal and non-small cell lung cancer, but little is known regarding the impact of anti-VEGF-A therapy on benign or premalignant tumors. The$Apc^{+/\text{min}}$mice have been widely used as a model recapitulating early i...

Alternative Titles

Full title

Inhibition of VEGF-A Prevents the Angiogenic Switch and Results in Increased Survival of$Apc^{+/\text{min}}$Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25435983

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25435983

Other Identifiers

ISSN

0027-8424

DOI

10.1073/pnas.0704213104

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